Team:Alberta-North-RBI E/projectsolution

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=='''OUR SOLUTION'''==
=='''OUR SOLUTION'''==
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As technologies continue to improve, there has been increasing interest in exploring the use of biomass as a renewable resource. Biomass is typically a by-product of an industrial process and considered waste. In particular, the by-product stream produced by paper recycling plants is presently disposed of via landfill or burnt. This is a significant source of potentially exploitable cellulose that can not only be used to produce high-value chemicals but will also have a positive impact on waste management.  
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As bio-processing technologies continue to improve, the use of biomass as a renewable resource will become more and more attractive. Biomass exists in many forms and is produced by diverse industrial processes. Paper recycling plants, in particular, generate a copious amount of waste biomass in the form of paper sludge. Costly disposal of this waste stream typically occurs via landfill, or through inefficient combustion. This is somewhat shocking because paper sludge is actually a significant source of valuable cellulose. Through our integrated bio-processing strategy, we can exploit this cellulose to produce high-value chemicals while simultaneously having a positive impact on waste management.  
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At '''Upcycled Aromatics''', work is underway on the design of an integrated bioprocessing facility. In conjunction with an enzymatic hydrolysis, engineered bacteria will transform the paper sludge waste stream into aromatic platform chemicals. The engineered bacteria will have the ability to produce a variety of aromatic chemicals - controlled by process conditions such that modification of one parameter results in the production of one specific chemical. The biosynthetic pathway under investigation will allow us to produce shikimic acid, cinnamic acid and it's derivatives.  
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Upcycled Aromatics is currently engineering bacteria which can transform the cellulose in the by-product stream into a series of aromatic platform chemicals. The designed organism will be controlled by process conditions to product different chemicals based on market demand. Our strain development will be based on synthetic biology principles, and more specifically on the BioBrick assembly standard. . The current proposed pathway will allow us to produce either Shikimic acid, Cinnamic acid, or Cinnamic acid derivatives.  
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Our solution is composed of two sections:
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The details of our solution can be found in two sections:  
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<html><a href="https://2012e.igem.org/Team:Alberta-North-RBI_E/process">Process</a></html>             
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<html><a href="https://2012e.igem.org/Team:Alberta-North-RBI_E/process">Process</a></html>  
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<html><a href="https://2012e.igem.org/Team:Alberta-North-RBI_E/genetics">Genetics</a></html>   
<html><a href="https://2012e.igem.org/Team:Alberta-North-RBI_E/genetics">Genetics</a></html>   
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Revision as of 22:23, 14 October 2012

OUR SOLUTION

As bio-processing technologies continue to improve, the use of biomass as a renewable resource will become more and more attractive. Biomass exists in many forms and is produced by diverse industrial processes. Paper recycling plants, in particular, generate a copious amount of waste biomass in the form of paper sludge. Costly disposal of this waste stream typically occurs via landfill, or through inefficient combustion. This is somewhat shocking because paper sludge is actually a significant source of valuable cellulose. Through our integrated bio-processing strategy, we can exploit this cellulose to produce high-value chemicals while simultaneously having a positive impact on waste management.

At Upcycled Aromatics, work is underway on the design of an integrated bioprocessing facility. In conjunction with an enzymatic hydrolysis, engineered bacteria will transform the paper sludge waste stream into aromatic platform chemicals. The engineered bacteria will have the ability to produce a variety of aromatic chemicals - controlled by process conditions such that modification of one parameter results in the production of one specific chemical. The biosynthetic pathway under investigation will allow us to produce shikimic acid, cinnamic acid and it's derivatives.

The details of our solution can be found in two sections:


Process

Genetics





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