Team:Alberta-North-RBI E

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==Success! Thanks!==
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University of Alberta's Upcycled Aromatics is proud and honoured to have won the 2012 iGEM E World Championship!
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Thanks everyone who supported Upcycled Aromatics, our sponsors, advisors and fellow iGEM'ers. All the hard work paid off, and certainly now there is a lot more work to be done!
==The Pitch==
==The Pitch==
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==Project Overview==
==Project Overview==
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New developments in synthetic biology have allowed scientists to explore innovative ways of producing important, high-value chemicals from what was once seen as industrial waste. In particular, paper recycling plants, as a byproduct of their operation, produce a waste sludge composed of paper fibres too short for further processing. This is a significant source of potentially exploitable cellulose. Aromatics represent a potentially lucrative chemical endpoint for this cellulose, having high price per unit mass and a sustainable market in both the pharmaceuticals and cosmetics industries. The conversion of this waste into valuable industrial chemicals is a relatively unexplored business opportunity and provides a unique niche which Upcycled Aromatics can fill.
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New developments in synthetic biology have allowed scientists to explore innovative ways of producing important, high-value chemicals from what was once seen as industrial waste. In particular, paper recycling plants, as a byproduct of their operation, produce a waste sludge composed of paper fibres too short for further processing. This is a significant source of potentially exploitable cellulose. Aromatics represent a potentially lucrative chemical endpoint for this cellulose, having high price per unit mass and a sustainable market in both the pharmaceuticals and cosmetics industries. The conversion of this waste into valuable industrial chemicals is a relatively unexplored business opportunity and provides a unique niche which '''Upcycled Aromatics''' can fill.
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Our company’s proposed process has two parts: in the first, cellulose from waste sludge from recycling plants is converted into glucose; in the second, glucose from the first part is used as a feedstock for the production of aromatic chemicals. The cellulose-glucose conversion will be done “on-site”. This glucose will be transported to a central headquarters, where it will be processed into a variety of aromatics for sale.
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Our company’s proposed process has two parts: in the first, cellulose from waste sludge from recycling plants is converted into glucose; in the second, glucose from the first part is used as a feedstock for the production of aromatic chemicals. The cellulose to glucose to products conversion will be done “on-site”. The products are high value aromatic compounds used in a variety of industries, including pharmaceuticals, food, fragrances and flavouring and specialty chemicals.
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In the glucose-aromatic conversion, we plan to use only a single metabolic pathway with “on and off switches” at each “step”. This gives us the freedom to produce any intermediary compounds in addition to the natural end product. The current proposed pathway will allow us to produce either shikimate or cinnamic acid derivatives using the method described above. Possible switch activators include temperature pH, or the addition of a inhibiting chemical such as phosphate.
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In the glucose to aromatics conversion, we plan to use only a single metabolic pathway with “on/off genetic switches” at different “steps” of the process. This gives us the freedom to produce any of three desired compounds as an end product: shikimate, cinnamic acid or 4-hydroxycinnamic acid. Possible switch activators include temperature pH, or the addition of a inhibiting chemical such as phosphate.
=='''Sponsors'''==
=='''Sponsors'''==
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Latest revision as of 02:40, 7 November 2012


Contents

Success! Thanks!

University of Alberta's Upcycled Aromatics is proud and honoured to have won the 2012 iGEM E World Championship! Thanks everyone who supported Upcycled Aromatics, our sponsors, advisors and fellow iGEM'ers. All the hard work paid off, and certainly now there is a lot more work to be done!

The Pitch

Project Overview

New developments in synthetic biology have allowed scientists to explore innovative ways of producing important, high-value chemicals from what was once seen as industrial waste. In particular, paper recycling plants, as a byproduct of their operation, produce a waste sludge composed of paper fibres too short for further processing. This is a significant source of potentially exploitable cellulose. Aromatics represent a potentially lucrative chemical endpoint for this cellulose, having high price per unit mass and a sustainable market in both the pharmaceuticals and cosmetics industries. The conversion of this waste into valuable industrial chemicals is a relatively unexplored business opportunity and provides a unique niche which Upcycled Aromatics can fill.


Our company’s proposed process has two parts: in the first, cellulose from waste sludge from recycling plants is converted into glucose; in the second, glucose from the first part is used as a feedstock for the production of aromatic chemicals. The cellulose to glucose to products conversion will be done “on-site”. The products are high value aromatic compounds used in a variety of industries, including pharmaceuticals, food, fragrances and flavouring and specialty chemicals.


In the glucose to aromatics conversion, we plan to use only a single metabolic pathway with “on/off genetic switches” at different “steps” of the process. This gives us the freedom to produce any of three desired compounds as an end product: shikimate, cinnamic acid or 4-hydroxycinnamic acid. Possible switch activators include temperature pH, or the addition of a inhibiting chemical such as phosphate.

Sponsors

Gold

Bronze



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